Cancer is the uncontrolled cell growth that can result in a tumor. Aflatoxin is a carcinogen in both animals and humans. Experimental evidence indicates that fumonisin is a promoter of cancer development.
Central nervous system refers to the brain and spinal cord. One of the responses to deoxynivalenol poisoning is an inflammation response in parts of the brain that control hunger, body temperature and movement.
Gastrointestinal refers to the stomach and intestines. Deoxynivalenol affects the gastrointestinal system. Consumption of the mycotoxin by monogastric animals can cause reduced weight gain and vomiting.
Hepatotoxicity is caused by damage to liver function. Both aflatoxin and fumonisin cause liver damage.
Hyperestrogenism is a condition caused by excessive amounts of estrogen. Zearalenone has estrogen-like properties, and consumption of the mycotoxin by swine can cause reduced conception, abortion, and uterine prolapse.
Immunosuppression is caused by mycotoxins that affect the immune system of animals. As a result, the affected animal has reduced resistance to pathogens and environmental pollutants. Aflatoxin is known to cause immunosuppression in some animals, including poultry.
Leukoencephalomalacia is disease in equine (horses) caused by fumonisin. Brain tissues of the affected animals become necrotic leading to symptoms that include tremors, ataxia, depression and death.
Nephrotoxicity is caused by damage to kidney function.
Pulmonary edema is a condition when fluids accumulate in the lungs. Fumonisin can cause pulmonary edemas in swine.
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